What is PRF?

PRF (platelet-rich fibrin) is an all-natural filler derived from your blood, rich in growth factors that stimulate collagen production and tissue regeneration. Unlike synthetic fillers, PRF gradually enhances skin texture, volume, and elasticity over time. It’s commonly used for under-eye rejuvenation, fine lines, and hair restoration. Because it’s 100% natural and free of additives, PRF provides a safe, biocompatible solution for those seeking subtle aesthetic improvements.

PRF corrects:

  • Under-eye hollows
  • Fine lines and wrinkles
  • Skin laxity
  • Acne scars
  • Hair thinning and loss
  • Volume loss in the face
  • Uneven skin texture
  • Dark circles

Your PRF journey

Procedure

Your provider will draw a small amount of your blood, which is then placed in a centrifuge to separate the platelet-rich fibrin. The PRF is carefully injected or applied to targeted areas using fine needles or a microneedling device. The procedure is quick and minimally invasive, with precise placement to stimulate collagen production and tissue regeneration. You may feel mild pressure or pinching, but the treatment is generally well-tolerated.

Recovery

You may experience mild swelling, redness, or bruising at the injection sites, which typically resolves within a few days. Since PRF is all-natural and derived from your own blood, the risk of adverse reactions is minimal. Recovery is quick, and you can resume most daily activities immediately. However, you should avoid strenuous exercise, excessive sun exposure, and certain skincare products for 24-48 hours for optimal healing and collagen stimulation.

Results

You may notice subtle improvements within a few weeks as PRF gradually stimulates collagen and tissue regeneration. Full results typically develop over 3-4 months. Since PRF enhances your skin naturally, results vary, but they can last 6-12 months. For optimal benefits, a series of treatments is recommended, usually spaced 4-6 weeks apart. You can maintain results with periodic maintenance sessions based on your provider’s recommendations.

How it works

PRF (platelet-rich fibrin) is derived from a small blood sample, spun at a low speed to separate platelets, fibrin, and white blood cells without additives or anticoagulants. This creates a fibrin matrix rich in growth factors that stimulate collagen production, tissue regeneration, and cellular repair. Once injected, PRF releases these growth factors, promoting natural skin rejuvenation and volume restoration. Unlike PRP, PRF forms a gel-like consistency, enhancing its ability to support skin structure while improving elasticity, hydration, and overall skin health over time.

Benefits of PRF:

  • 100% natural filler with no additives or synthetic ingredients
  • Gradual release of growth factors for longer-lasting effects
  • Stimulates collagen production and tissue regeneration
  • Improves skin texture, elasticity, and hydration
  • Enhances volume in a subtle, natural-looking way
  • Minimizes risk of allergic reactions or complications
  • Uses the body’s own healing properties for biocompatibility
  • Ideal for patients seeking a more natural alternative to synthetic fillers

Why Buffalo Aesthetics?

Buffalo Aesthetics is a luxurious, physician-led cosmetic medical spa dedicated to delivering natural, high-quality aesthetic results. Our expert team combines advanced techniques with personalized care to enhance your skin’s health and beauty. Whether you’re looking for subtle rejuvenation or a comprehensive transformation, please schedule a consultation today to discover how PRF can enhance your natural beauty.

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